Efficiency of mepivacaine 2% versus lignocaine 2% in the extraction of impacted third molars: Randomized, clinical trial

Zameer Pasha, Zuber Ahmed Naqvi, Saleem Shaikh, Milton Carlos Kuga
2017 International Dental & Medical Journal of Advanced Research - VOLUME 2015  
Most commonly performed the minor oral surgical procedure is removal of a lower third molar. And to ease this procedure many local anesthetics are available, and the commonly used local anesthetics are lignocaine with adrenaline, but recently mepivacaine with levonordefrin is used as it is longer acting than lignocaine with the same concentration. However, very less clinical studies have been conducted to compare these two to know the efficacy and depth or anesthesia. Aim: Purpose of the study
more » ... rpose of the study is to compare the efficiency of mepivacaine 2% with levonordefrin versus lignocaine 2% with adrenalin in the extraction of bilaterally impacted third molars: A single-blind, clinical trial. Materials and Methods: In the study, 128 patients were selected with all types of mandibular third molar impactions. Inferior alveolar nerve block is given with mepivacaine 2% with levonordefrin or lignocaine 2% with adrenalin surgical procedure was started 5 min after anesthesia is achieved . Result: The mean onset of anesthesia in mepivacaine group is 4.38 and in lignocaine group is 4.86. Moreover, mean duration of anesthesia in Group A 170.31 min and 168.72 min in Group B. There is statistically significant difference in the depth of anesthesia in-Group A and Group B intraoperatively, in-Group A 28 (43.7%) patient experienced pain during a procedure on visual analog scale, whereas in-Group B 9 (14.06%). Conclusion: In our study mepivacaine with levonordefrin has inferior performance in relation to lignocaine with adrenaline in terms of depth of anesthesia. Clinical Significance: Literature says mepivacaine with levonordefrin is better than lignocaine with adrenaline in duration of action and in depth of anesthesia, but clinically we found there is no statistically difference in duration and in depth of anesthesia, we found lignocaine with adrenaline is better.
doi:10.15713/ins.idmjar.80 fatcat:euj6ujy4vjdsfdwzptspzvmcpq