Response to cryptorchidism of the testis and epididymis of the opossum (Didelphis virginiana)

J. N. Scott, H. I. Fritz, F. Nagy
1979 Reproduction  
Adult male opossums, Didelphis virginiana, were rendered hemicryptorchid for 35 days. The cryptorchid testis exhibited a significant reduction in weight, while the contralateral testis had a compensatory weight gain compared with testes of untreated animals. Histological changes in the cryptorchid testis included fibrosis of the tunica propria, involution of the seminiferous tubules and an apparent increase in the interstitial tissue. Many seminiferous tubules were empty and germinal cells were
more » ... germinal cells were absent. Some Sertoli cells persisted, but the cytoplasm was vacuolated. Cryptorchid testes were characterized by mononuclear leucocytic invasion around the tubules, and some eosinophils were observed. Cryptorchidism in the opossum may induce a reaction similar to experimental orchitis.
doi:10.1530/jrf.0.0570175 pmid:41944 fatcat:bdym4sxmxfgtxfhtlwzptb7fse