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Anti-Oxidant Effect of Infliximab and DMF During Ischemia Reperfusion Induce Liver Injury in Male Rat
Journal of Pharmaceutical Negative Results
Ischemia-reperfusion injury (IRI) to the liver causes inflammatory and oxidative stress events, as well as hepatocyte apoptosis and liver injury. In this study, we investigated whether infliximab, DMF, and their combination reduced ROS production in rat livers and played a protective role in the pathogenesis of I/R-induced liver injury in rats. Aim: study the role of infliximab, DMF, and their combination in hepatic I/R injury. Methods: 5 groups of 40 male rats were randomized in the followingdoi:10.47750/pnr.2021.13.03.103 fatcat:d4hpanwjj5ekrdxej55r6y63yi