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Genomic investigation of etiologic heterogeneity: methodologic challenges
2014
BMC Medical Research Methodology
The etiologic heterogeneity of cancer has traditionally been investigated by comparing risk factor frequencies within candidate sub-types, defined for example by histology or by distinct tumor markers of interest. Increasingly tumors are being profiled for molecular features much more extensively. This greatly expands the opportunities for defining distinct sub-types. In this article we describe an exploratory analysis of the etiologic heterogeneity of clear cell kidney cancer. Data are
doi:10.1186/1471-2288-14-138
pmid:25532962
pmcid:PMC4292824
fatcat:svp3wwurlrea7fibpv25lpawgu