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High-throughput analysis of adaptation using barcoded strains of Saccharomyces cerevisiae
2020
PeerJ
Experimental evolution of microbes can be used to empirically address a wide range of questions about evolution and is increasingly employed to study complex phenomena ranging from genetic evolution to evolutionary rescue. Regardless of experimental aims, fitness assays are a central component of this type of research, and low-throughput often limits the scope and complexity of experimental evolution studies. We created an experimental evolution system in Saccharomyces cerevisiae that utilizes
doi:10.7717/peerj.10118
pmid:33088623
pmcid:PMC7571412
fatcat:256xzzhph5eonllgirzp2c2nvu