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References Reply to Payne et al The letter of Payne et al gives some results on plasma ACE activity and I/D genotype frequency according to the presence or absence of angiographically proven coronary heart disease. These results are, as far as we are aware, the first ones published in the literature, and some degree of parallelism with ours is striking. However, because of the large clinical heterogeneity of people by guest on August 17, 2017 http://circ.ahajournals.org/ Downloaded from J Edoi:10.1161/01.cir.90.5.2567 pmid:7955224 fatcat:tsfdtnmaqbgj5kas6m7foul4ki