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Hot-water-extracts of Polygonum Multiflorum Do Not Induce Any Toxicity but Elicit Limited Beneficial Effects on the Liver in Mice
Journal of health science
Shou-Wu-Pian, a herbal remedy formulated from Polygonum multiflorum (PM), has been extensively used for the treatment of hair-loss, constipation and vertigo in Asia, Europe and U.S.A. Although recent reports have indicated severe liver damage occurred after taking Shou-Wu-Pian in humans, studies on the hepatotoxicity of this herbal remedy have been limited, and this organ-specific adverse effect induced by PM intake remains to be confirmed. In this study, hepatotoxicity of hot-water-extracteddoi:10.1248/jhs.55.720 fatcat:rd5lecxtanavvd6dkywhs2xkn4