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A systematic approach to managing symptoms related to advanced oncological illness can improve patient quality of life and lessen distress. Lisa Scholder. Sunlit Legs. 16" × 22". Photo courtesy of Lisa Scholder. Background: Advanced cancer produces multiple symptoms as patients progress through their disease trajectory. Identifying, measuring, and providing therapy for uncontrolled symptoms becomes important because disease-altering therapies may be no longer possible. Symptoms other than paindoi:10.1177/107327481502200406 pmid:26678967 fatcat:o4whkqpwpjd47did5xghuzp3dy