Evaluation of body mass index and lipid fractions levels in patients with retinal artery occlusion

Dijana Risimic, Dejan Nikolic, Vesna Jaksic, Dejan Simeunovic, Svetislav Milenkovic, Ivan Stefanovic, Natasa Jakovic, Nada Milic, Sonja Cekic, Sinisa Babovic
2011 Vojnosanitetski Pregled  
Background/Aim. There are studies stressing out that atherosclerosis is most common associated systemic condition in patients with retinal artery occlusion. The aim of this study was to analyze values of body mass index and lipid fractions in healthy individuals and patients with retinal artery occlusion. Methods. This study included 90 participants during a 6-year period. The population was divided into 2 groups: the group with the diagnosed retinal artery occlusion and the group without
more » ... group without retinal artery occlusion. The observed parameters were as follows: body mass index, low and high density lipoproteins and triglycerides. Results. The study revealed no significant difference regarding body mass index and triglycerides values between the two evaluated groups, while low and high density lipoproteins values were significantly higher in the group of patients with retinal artery occlusion. Conclusions. The study demonstrated that body mass index and triglycerides have less important role in atherogenic pathogenesis of retinal artery occlusion, while low density lipoprotein is the fraction that is shown to be most potent in such etiological processes. Key words: arteriosclerosis; lipids; body mass index; retinal artery; arterial occlusive diseases. Apstrakt Uvod/Cilj. Studije svetskih autora ističu da je ateroskleroza najčešće sistemsko stanje udruženo sa okluzijom arterijskih krvnih sudova retine. Cilj ove studije bio je analiza vrednosti indeksa telesne mase i lipidnih frakcija kod zdravih osoba i bolesnika sa okluzijom retinalne arterije. Metode. Ova studija obuhvatila je 90 osoba tokom 6-godišnjeg perioda. Ispitanici su bili podeljeni u dve grupe: grupu sa dijagnostikovanom okluzijom retinalne arterije i grupu bez okluzije retinalne arterije. Ispitivani su sledeći parametri: indeks telesne mase, lipoproteini male i velike gustine i trigliceridi. Rezultati. Dobijeni rezultati pokazali su da ne postoji značajna razlika u vrednostima indeksa telesne mase i triglicerida između ispitivanih grupa, dok su lipoproteini male i velike gustine bili značajno povišeni kod osoba sa okluzijom retinalne arterije. Zaključak. Indeks telesne mase i trigliceridi imaju manju ulogu u procesima aterogeneze kod okluzije retinalnih arterija, dok su lipoproteini male gustine značajan faktor u procesu koji vodi okluzivnim promenama ovih krvnih sudova.
doi:10.2298/vsp1103231r pmid:21524005 fatcat:irj4ftjswvhqbb7qazj2lmdkia