Comparative serum testing by the Wassermann reaction using cardiolipin and standard antigens was reported by Price and Wilkinson (1950). Test results on 5,124 sera were reviewed and it was concluded that cardiolipin antigen was appreciably more sensitive than the standard antigen (Harrison and Wyler technique), as it detected a higher proportion of cases of early primary syphilis and also remained positive in cases of treated syphilis long after other tests had reverted to negative. In the

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... ng of problem sera sent to the V.D. Reference Laboratory, cardiolipin antigen was more specific than the standard antigen (940 sera tested). In