Gingival recession remains a widespread finding in the general patient population. A placenta-derived membrane has been introduced for treatment of recession defects but it has not been studied in comparison to acellular dermis matrix. The purpose of this case series was to evaluate results of coronally advanced flap surgery using placentaderived membranes (PM) compared to acellular dermis matrix (ADM). A split-mouth design was used in this study with 60 contralateral sites in 8 patients with

more »

... ller Class I or II recession sites. 30 sites were treated with placenta-derived membranes and were compared to 30 sites treated with acellular dermal matrix, both done with a coronally positioned flap technique. Enamel matrix derivative was applied to all root surfaces after root planing and treatment with EDTA. Clinical parameters recorded at baseline and after three months were vertical recession (VR), probing depth (PD), clinical attachment level (CAL) and keratinized tissue width (KT). Results: Both groups showed significant recession coverage, decreased probing depth, increased clinical attachment gain but minimal increased width of keratinized gingiva. The percentage of root coverage was 84% for the ADM-treated sites, and 57% for the PM sites. Clinical attachment gain was 2.4 mm for PM and 3.0 mm for ADM. The differences in vertical root coverage were statistically significant. Based on the results of this study, both materials were effective in gaining vertical root coverage and increasing clinical attachment, with the acellular dermis matrix material showing a statistically significant greater amount of root coverage.