System level visualization of eQTLs and pQTLs

Joanna Jakubowska, Ela Hunt, Matthew Chalmers, David Leader, Martin McBride, Anna F Dominiczak
2005 BMC Bioinformatics  
Effective visualisation of syntenic genome areas and QTLs derived from physiological and expression data is an unresolved issue. We are investigating genomic visualizations including SyntenyVista2 and Der Browser3 in order to establish the best way to integrate and display these data, and support the use of synteny in the identification of genes responsible for cardiovascular phenotypes. We are showing information regarding eQTLs and pQTLs for the rat1 integrated with data from Ensembl. Initial
more » ... data representation uses Der Browser. We are also integrating the addition of further data from the MGI, OMIM and RGD. In the next step we will serve these data using Syn-tenyVista and possibly some other package.
doi:10.1186/1471-2105-6-s3-p15 fatcat:yimv7csc4rbwblfsfyftm4h6fy