The investigation was carried out to determine the antimicrobial activity of the Leaf and Root extracts of Kigelia africana (nonon giwa) and Albizia chevalieri (katsari) against Staphylococcus aureus. Antimicrobial activity was evaluated by disc diffusion method and MIC and MBC were calculated by double fold dilution method. The antimicrobial activity result shows 20mm zone of inhibition Kigelia africana leaf at 100% concentration and 16mm zone of inhibition for albezia chevalieri leaf at same

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... oncentration while for the roots 14mm and 11mm zone of inhibition at 100% concentration. The maximum inhibition zone is found at 20mm and minimum inhibition zone at 11mm. Also the antimicrobial result shows the MIC of 6.25mg/ml against Staphylococcus aureus and MBC of 12.5mg/ml and 10.5mg/ml for both extracts. The study reveals that the extracts possess antimicrobial activity in a dose dependent manner. This antimicrobial activity may be due to the presence of some active compounds, further studies are highly needed for the drug development.