Clinical features and efficacy of antiviral drug, Arbidol in 220 nonemergency COVID‐19 patients from East-West-Lake Shelter Hospital in Wuhan: a retrospective case series

Wei Gao, Si Chen, Kun Wang, Rongzhang Chen, Qian Guo, Jingjing Lu, Xiaodong Wu, Yanan He, Qiaoyun Yan, Shengyun Wang, Feilong Wang, Li Jin (+2 others)
2020 Virology Journal  
Objective We aimed to describe the features of 220 nonemergency (mild or common type) COVID-19 patients from a shelter hospital, as well as evaluate the efficiency of antiviral drug, Arbidol in their disease progressions. Methods Basic clinical characteristics were described and the efficacy of Arbidol was evaluated based on gender, age, maximum body temperature of the patients. Results Basically, males had a higher risk of fever and more onset symptoms than females. Arbidol could accelerate
more » ... could accelerate fever recovery and viral clearance in respiratory specimens, particularly in males. Arbidol also contributed to shorter hospital stay without obvious adverse reactions. Conclusions In the retrospective COVID-19 cohort, gender was one of the important factors affecting patient's conditions. Arbidol showed several beneficial effects in these patients, especially in males. This study brought more researches enlightenment in understanding the emerging infectious disease.
doi:10.1186/s12985-020-01428-5 pmid:33097047 fatcat:v7zhz4aj4reyhaeuetd5sse4ti