OSTEOPOROSIS IN LIVER CIRRHOSIS
Liver cirrhosis is highly prevalent in developing countries like Pakistan and osteoporosis is well reported and can add to further morbidity in such cases. Objective; To determine the frequency of osteoporosis in cases of liver cirrhosis. Methods; This cross sectional study was done at outpatient department of RHC Jhawaria, THQ shahpur and RHIC Khabeki during July to December 2018. The patients with age 30-70 years having liver cirrhosis of at least 1 year or more were included. The detailed
... iodemographic and clinical data was collected and osteoporosis was labeled as yes when the T score was less than 2.5 on DEXA scan. Results; In this study there were total 200 cases out of which 124 (62%) males and 76 (38%) females with mean age of 44.35±8.32 years. Osteoporosis was seen in 68 (34%) of cases. Osteoporosis affect more females where it was seen in 32 (42.10%) out of 76 cases with p= 0.09. Osteoporosis was significantly high (p=0.002) in cases that had cirrhosis more than 3 year affecting 56 (46.67%) cases in contrast to 12 (15%) cases in their respective groups. There was no difference regarding type of hepatitis between both groups (table 2). Conclusion; Osteoporosis is common in cases of liver cirrhosis where every 3rd cases develops it and duration of cirrhosis more than 3 years is significantly associated with this. Key words: Liver cirrhosis, osteoporosis, T score, DEXA scan.