Comparison of Ceramide Monohexoside and Sulfatide in Brain and Liver of Japanese Pilchard (Sardines)

Nobuko TANAKA, Hiroshi OKAMURA
1999 Journal of Japan Oil Chemists Society  
Comparative study is effective for clarifying differences in animal species in regard to the physiological functions of glycosphingolipid. Determination was thus made of the molecular structure of CMH present at high concentrations in the brain of sardines by GLC analysis for comparison with CSE in the brain and CMH in the liver. CMH content in the brain of sardines is lower than in that of mammals. There is species specificity in this regard. The principal fatty acid of CMH and CSE have carbon
more » ... and CSE have carbon chains of 24. There is no difference between sardines and mammals. The unsaturation of constituting fatty acids of CSE and CMH in the brain is higher than in mammals (72.4% vs. 67.5%). Contrary to brain, fatty acids of CMH in the liver indicates low degree of the unsaturation and high ratio of the hydroxy fatty acid (88.9%). There is organ specificity in this regard. The sugars of CSE and CMH in the brain were mostly galactose, suggesting galactose to be more important for all animal species. In CMH in the liver, glucose was present at 26.2%. Long chain bases were comprised mainly of sphingosine (the order of 70%) like mammals.
doi:10.5650/jos1996.48.693 fatcat:yf26ffmebnae7ehwm4ohlpiq7y