Unexpected Insertion Reaction of Dimethoxycarbene with Imidazole-2(3H)-thiones

Grzegorz Mlostoń, Heinz Heimgartner
2010 Phosphorus Sulfur and Silicon and the Related Elements  
The reaction of in situ generated dimethoxycarbene with 1,4,5-trisubstituted imidazole-2(3H)thiones yields 3-(dimethoxymethyl)imidazole-2(3H)-thiones in good yield via insertion into the N-H bond. The structure of the products was established by spectroscopic data and, in the case of 7b, by X-ray crystallography.
doi:10.1080/10426501003773761 fatcat:3xqhy7b3ozc63glk2amqshlake