The fourth scientific discovery paradigm for precision medicine and healthcare: challenges ahead

Li Shen, Jinwei Bai, Jiao Wang, Bairong Shen
2021 Precision Clinical Medicine  
With the progression of modern information techniques, such as the next generation sequencing (NGS), Internet-of-Things (IoT) based smart sensors and artificial intelligence algorithms, the data-intensive research and application now is emerged as the fourth paradigm for scientific discovery. However, we are still facing many challenges to apply this paradigm practically. In this review, ten challenges about the data-intensive discovery and applications in precision medicine and healthcare are
more » ... ummarized and the future perspectives on the next generation medicine are discussed.
doi:10.1093/pcmedi/pbab007 pmid:35694156 pmcid:PMC8982559 fatcat:lgtgfo2lqrbtrkt2amnck2ygtm