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Use of serum antibody and lysozyme levels for diagnosis of leprosy and tuberculosis
Journal of Clinical Microbiology
Active tuberculosis (TB) and leprosy are difficult to diagnose early because there are few organisms to detect and the specific immune response does not distinguish between active and inactive disease. We developed an immunoassay for lysozyme to see whether serum lysozyme levels could be used to identify individuals with clinical leprosy or TB. The immunoassay for lysozyme proved superior to standard enzyme assays that were less sensitive and reliable. The lysozyme assay was compared withdoi:10.1128/jcm.30.5.1105-1110.1992 fatcat:essq5y2zkffb3gekfarxzi7mm4