Neonatal meningitis and ventriculitis caused by Enterobacter cloacae after surgery for jejunal atresia
空腸閉鎖術後にEnterobacter cloacaeによる髄膜炎・脳室炎を合併し広範な大脳壊死を生じた新生児例

Kiichi Takahashi, Hiroyuki Adachi, Masato Ito, Akie Kato, Taku Hebiguchi, Tsutomu Takahashi
2020 Journal of Japan Society of Perinatal and Neonatal Medicine  
Enterobacter cloacae, a gram-negative bacillus, is a member of the normal gut microbiota; however, it is often highly virulent in neonates. Notably, neurological sequelae of meningitis may occur despite the administration of systemic antibiotics. We describe a female neonate weighing 2 , 309 g born at 33 weeks and 4 days of gestation who developed E. cloacae meningitis and ventriculitis after undergoing surgery for jejunal atresia. She developed severe cerebral necrosis despite treatment with
more » ... gh-dose carbapenem. We speculated that bacterial translocation of E. cloacae secondary to surgical injury caused meningitis and ventriculitis. E. cloacae can rapidly colonize the gut in neonates soon after birth; therefore, early identification of this highly pathogenic organism is important to initiate prompt and optimal infection control measures, particularly in neonates undergoing gastrointestinal surgery.
doi:10.34456/jjspnm.56.2_335 fatcat:wkt4hhj4mjg5biwm4etkdewbqe