Objective: To study the frequency and distribution of odontogenic tumors (OTs) and their clinico-pathological features among South Indian sample population by analyzing biopsy specimens obtained from the archives . Study design: Data for the study were retrieved from the case records of patients and the analyzed clinical variables included age, gender and anatomical location. Histopathological features of the lesions were reevaluated and those fitting the World Health Organization (2005)

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... gical classification for odontogenic tumors, including Kerato Cystic Odontogenic tumor (KCOT) were analyzed in the study. Results: Of the 3148 biopsy reports analyzed, 111 cases (3.52%) were odontogenic tumors, including ameloblastoma (52.2%), KCOT (27.9%), odontogenic myxoma (6.3%), adenomatoid odontogenic tumor (5.4%), odontoma (2.7%), calcifying epithelial odontogenic tumor (1.8%), ameloblastic fibroma (1.8%), ameloblastic fibro dentinoma (0.9%), and odontogenic fibroma (0.9%). All were benign and the patients affected were over a wide range of age group, 11-80 years with mean age being 32.12 years and the peak incidence was seen in the second, third and fourth decades of life. Mandible (73.9%) was the site of predilection, with slight male predominance (57.6%). Ameloblastoma is the most frequent odontogenic tumor followed by KCOT in this study. Including KCOT under odontogenic tumors, has numerically raised the overall percentage of OTs and brought down the percentage of individual lesions, in particular ameloblastoma. The concept of presence of geographic and regional variations in the occurrence of odontogenic tumors is favored by the study results.