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Experimental immunology Cytotoxic and immunotoxic effects of the mixture containing cyanotoxins on carp cells following in vitro exposure
Central European Journal of Immunology
Additive, synergistic or antagonistic effects of various types of cyanotoxins have so far not been investigated. The aim of this study was to assess the potential synergistic effects of microcystin-LR and anatoxin-a on immune cells isolated from the common carp (Cyprinus carpio L.). Cytotoxicity of the toxin mixture to leukocytes, its influence on lymphocyte proliferation, as well as phagocytosis and intracellular production of reactive oxygen species by phagocytes were assessed. The membranedoi:10.5114/ceji.2013.35207 fatcat:kvzu4q3ayjf4za6ioco3dvai24