A size‐adaptive 32‐channel array coil for awake infant neuroimaging at 3 Tesla MRI

Anpreet Ghotra, Heather L. Kosakowski, Atsushi Takahashi, Robin Etzel, Markus W. May, Alina Scholz, Andreas Jansen, Lawrence L. Wald, Nancy Kanwisher, Rebecca Saxe, Boris Keil
2021 Magnetic Resonance in Medicine  
Functional magnetic resonance imaging (fMRI) during infancy poses challenges due to practical, methodological, and analytical considerations. The aim of this study was to implement a hardware-related approach to increase subject compliance for fMRI involving awake infants. To accomplish this, we designed, constructed, and evaluated an adaptive 32-channel array coil. To allow imaging with a close-fitting head array coil for infants aged 1-18 months, an adjustable head coil concept was developed.
more » ... The coil setup facilitates a half-seated scanning position to improve the infant's overall scan compliance. Earmuff compartments are integrated directly into the coil housing to enable the usage of sound protection without losing a snug fit of the coil around the infant's head. The constructed array coil was evaluated from phantom data using bench-level metrics, signal-to-noise ratio (SNR) performances, and accelerated imaging capabilities for both in-plane and simultaneous multislice (SMS) reconstruction methodologies. Furthermore, preliminary fMRI data were acquired to evaluate the in vivo coil performance. Phantom data showed a 2.7-fold SNR increase on average when compared with a commercially available 32-channel head coil. At the center and periphery regions of the infant head phantom, the SNR gains were measured to be 1.25-fold and 3-fold, respectively. The infant coil further showed favorable encoding capabilities for undersampled k-space reconstruction methods and SMS techniques. An infant-friendly head coil array was developed to improve sensitivity, spatial resolution, accelerated encoding, motion insensitivity, and subject tolerance in pediatric MRI. The adaptive 32-channel array coil is well-suited for fMRI acquisitions in awake infants.
doi:10.1002/mrm.28791 pmid:33829546 fatcat:o7dj6laye5e65fbqkmylcz3vc4