A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is
FcϵRI and Thy-1 domains have unique protein and lipid compositions
Journal of Lipid Research
Receptor activation leads to the dynamic remodeling of the plasma membrane. Previous work using immunoelectron microscopy showed that aggregated high-affinity receptor for immunoglobulin E (FceRI) and aggregated Thy-1, a glycerophosphoinositol (GPI)-anchored protein, have distinct membrane distributions. We now report lipidomics analysis of FceRI-and Thy-1-enriched vesicles obtained by magnetic bead isolation in the absence of detergent. Protein analyses show that FceRI domains are enriched indoi:10.1194/jlr.m600485-jlr200 pmid:17387221 fatcat:w6f3s7xz3zasvpmdoo6grdj7hq