Recovery from Rheumatoid Cerebral Vasculitis by Low-Dose Methotrexate

Tatsuharu OHNO, Isao MATSUDA, Hiroo FURUKAWA, Tadashi KANOH
1994 Internal medicine (Tokyo. 1992)  
Wereport the successful managementof cerebral vasculitis in a 46-year-old womanwith longstanding rheumatoid arthritis with low-dose methotrexate. She suddenly developed dysarthria and left hemiparesis. Magnetic resonance imaging disclosed ischemia of the right pons, and angiography demonstrated cerebral vasculitis of vertebro-basilar arteries. The vasculitis was refractory with high-dose steroid therapy, which had only transient clinical benefit, and evolution to the pontine infarction
more » ... Her clinical status showed marked improvement in association with recovery of the vascular abnormalities after the initiation of the methotrexate therapy. (Internal Medicine 33: 615-620, 1994)
doi:10.2169/internalmedicine.33.615 fatcat:6ey2yl53ybgtzkpfe2rkhoexiu