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Anticholinergic Drugs – Functional Antidotes for the Treatment of Tabun Intoxication
1. To study the influence of antidotes on tabun-induced neurotoxicity, the rats were injected intramuscularly with organophosphate tabun (LD50). The efficacy of choice antidotal treatment consisting of acetylcholinesterase reactivator obidoxime and one of four anticholinergic drugs (atropine, benactyzine, biperiden, scopolamine) was compared. 2. Testing of tabun-induced neurotoxicity progress was carried out using the method Functional observational battery. The experimental animals as well asdoi:10.14712/18059694.2018.59 fatcat:5by3gqvsxbbvdiwvwyb7z2b5mi