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Multivariate cellular image-based drug profiling to identify synergistic drug combinations for the treatment of triple-negative breast cancer
[thesis]
2013
Triple-negative breast cancer (TNBC) is the most aggressive form of breast cancer. Due to the lack of known receptors, these tumours are resistant to tailored therapies and the standard of care is therefore limited to combinations of chemotherapy agents. These therapies are frequently plagued with intrinsic and acquired drug resistance, highlighting the need for novel and more effective combinations. However, cost- and time-limiting aspects of assessing the large number of possible combinations
doi:10.26190/unsworks/2481
fatcat:hm3djuc7cjbidabd4mgvbhkyx4