THU0212 Imbalance between synovial il-1 activity/il-1ra production and disease course in rheumatoid arthritis

H Fenner, S Zueger, M Schattenkirchner
2001 Speaker abstracts 2001   unpublished
be updated easily at each visit, without a need to collect the data again. Results The CLUE forms have been used to characterise 102 consecutive patients with RA in routine clinical care. Medications in current use included prednisone (median dose 4 mg per day) by 94% of patients, methotrexate (median dose 15 mg per week) by 86%, hydroxycholoroquine by 28%, leflunomide by 10%, cyclosporine by 8%, etanercept by 8%, infliximab by 8%, auranofin by 3%, gold injections by 3%, azathioprine by 2%,
more » ... hioprine by 2%, penicillamine by 1%, and sulfasalazine by 1% of patients. Extraarticular disease included malaise reported by 72% of patients, dry mouth by 46%, carpal tunnel syndrome 37% dry eyes by 35%, and scleritis by 9% of patients at any time in the course of RA. Comorbities included chronic back pain in 36% of patients, hypertension in 31%, peptic ulcer in 27%, esophageal symptoms in 25%, cataract in 20%, thyroid disease in 11%, cancer in 10%, diabetes mellitus in 4%, renal disease in 3% of patients. Sixty-three percent of patients had smoked cigarettes and 28% were current smokers. Conclusion Two simple clinical longterm updateable evaluation (CLUE) forms are easily completed in usual clinical care to characterise patients with RA. These forms are complemented by a patient questionnaire and joint count form, to provide simple, standardised measures of RA for improved clinical care, clinical research, and clinical outcomes.
doi:10.1136/annrheumdis-2001.1114 fatcat:x7djizxmqrectkknfbwy47fsyi