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Leptin in functional hypothalamic amenorrhoea
BACKGROUND: Leptin, body weight, body mass index (BMI) and other hormones in women with functional hypothalamic amenorrhoea (FHA) were investigated and the hypothesis proposed that energy imbalance is the predominant mechanism for leptin reduction in patients with FHA. METHODS: Eighty-eight women with FHA and 65 age-and weight-matched controls were divided into homogeneous groups on the basis of their BMI: women with different degrees of underweight (BMI 15-16, 17-18 kg/m 2 ) and of normaldoi:10.1093/humrep/17.8.2043 pmid:12151434 fatcat:55nbzf24tzewzlazpkoylfcywu