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Septins are GTP-binding proteins that form ordered, rod-like multimeric complexes and polymerize into filaments, but how such supramolecular structure is related to septin function was unclear. In Saccharomyces cerevisiae, four septins form an apolar hetero-octamer (doi:10.1016/j.devcel.2011.02.004 pmid:21497764 pmcid:PMC3079881 fatcat:ppksbcagobb33pwyy7ioirypx4