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The biomarkers related to immune related adverse events caused by immune checkpoint inhibitors
2020
Journal of Experimental & Clinical Cancer Research
AbstractThe enthusiasm for immune checkpoint inhibitors (ICIs), an efficient tumor treatment model different from traditional treatment, is based on their unprecedented antitumor effect, but the occurrence of immune-related adverse events (irAEs) is an obstacle to the prospect of ICI treatment. IrAEs are a discrete toxicity caused by the nonspecific activation of the immune system and can affect almost all tissues and organs. Currently, research on biomarkers mainly focuses on the
doi:10.1186/s13046-020-01749-x
pmid:33317597
fatcat:fgtecfayx5bpvkftzthf7bfcva