Recent Progresses in Brain Gene Therapy

Afsoun Seddighi, Amir Nikouei, Amir Saied Seddighi, Mohammad Asadpour, Noushin Masoudian, Afshin Samaie
2016 International Clinical Neuroscience Journal  
Gene therapy consists of the introduction of genetic material into cells for a therapeutic purpose. The understanding of the basics of the molecular and cellular mechanisms in disease treatments has resulted in the development of high-tech gene transfer materials with improved therapeutic efficacy. Based on the results of more than 2000 clinical trials to date, gene therapy is going to be included in standard treatment approaches in some specific diseases. Also, gene therapy has been highly
more » ... has been highly improved in central and peripheral nervous system diseases. This review tried to focus on techniques and approaches in brain tumors and nervous system's gene therapy strategies and will discuss about associated problems and potential future in management of inherited or acquired neurological disorders.
doi:10.22037/icnj.v3i4.14981 doaj:a98866ba72b143c99785851879f1ba9a fatcat:kfcamvuaargrppnyv6capfk4py