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Objectives Adolescent risk behaviours are a key health concern. The purpose of this research is to gaina deeper understanding of how, why, for whom, and inwhat circumstances complex adolescent risk behaviourprevention programmes are most successful. Methods and analysis To understand how adolescent risk behaviour prevention programmes work in a reallife context, a realist synthesis will be undertaken, operationalised in four phases.doi:10.1136/bmjopen-2016-015477 pmid:28939568 pmcid:PMC5623505 fatcat:b3aaedffyfcclfvtgdhjhvgiv4