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Improved antitumor efficacy of neutrophils stimulated by bacillus Calmette‑Gu�rin
2019
Molecular Medicine Reports
Bacillus Calmette‑Guérin (BCG) has become a significant treatment for bladder cancer, and neutrophils are reported to be associated with the antitumor effect of BCG. The aim of the present study was to clarify the antitumor function of neutrophils stimulated by BCG. Initially, the killing effect and cytotoxic activity of neutrophils treated with BCG was detected. Subsequently, the effectiveness of BCG‑treated neutrophils extracted from tumor‑bearing mice was analyzed. The results revealed that
doi:10.3892/mmr.2019.10532
pmid:31524238
fatcat:btdpm3hoffbk7j3c7rmlk4ivje