Copper-based wood preservatives such as CCA, CCB, AZCA, have long been used because of their considerable efficacy. Although copper-based wood preservatives have been widely used for protecting wood against fungal attack, some brown rot and soft rot fungi, have repeatedly been isolated from copper treated wood in service, although CCA contains arsenic which is very toxic to fungi and insects. Copper tolerance in Poria species converted soluble copper sulphate into insoluble copper oxalate,

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... is less toxic to fungi. Especially, wood materials used in ground contact and in the regions where the decay risk of wood materials is higher result in more leaching, these factors should be taken into account and also additional fungicides might be thought to be added into preservatives formulations.