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Corpus Callosum Atrophy Is a Possible Indicator of Region– and Cell Type–Specific Neuronal Degeneration in Alzheimer Disease
1998
Archives of Neurology
Preserved Fulltext
Pathological studies in Alzheimer disease indicate the specific loss of layer III and V large pyramidal neurons in association cortex. These neurons give rise to long corticocortical connections within and between the cerebral hemispheres. Objective: To evaluate the corpus callosum as an in vivo marker for cortical neuronal loss.
doi:10.1001/archneur.55.2.193
pmid:9482361
fatcat:h76az2jswndr3jd35dylx7gkpu