New Methods in Diffusion-Weighted and Diffusion Tensor Imaging

Roland Bammer, Samantha J. Holdsworth, Wouter B. Veldhuis, Stefan T. Skare
2009 Magnetic Resonance Imaging Clinics of North America  
Synopsis Considerable strides have been made by countless individual researchers in diffusion-weighted imaging (DWI) to push DWI from an experimental tool -limited to a few institutions with specialized instrumentation -to a powerful tool used routinely for diagnostic imaging. Despite its current success, the field of DWI constantly evolves and progress has been made on several fronts, awaiting adoption by vendors and clinical users to bring in the next generation of DWI. These developments are
more » ... primarily comprised of improved robustness against patient and physiologic motion, increased spatial resolution, new biophysical and tissue models, and new clinical applications for DWI. This article aims to provide a succinct overview of some of these new developments and a description of some of the major challenges associated with DWI. Trying to understand some of these challenges is helpful not only to the technically savvy MRI user, but also to radiologists who are interested in the potential strengths and weaknesses of these techniques, what is in the "diffusion pipeline", and in how to interpret artifacts on DWI scans.
doi:10.1016/j.mric.2009.01.011 pmid:19406353 pmcid:PMC2768271 fatcat:6ghbmckysvcprnmbewpzujjkpm