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56 This article considers the present state and prospects of Russian-Lithuanian cooperation in the field of research and innovation. The author analyses the tendencies of innovation activities of economic entities in the North-West of Russia in terms of relative innovation activity indicators. Special attention is paid to the role of cross-border and trans-border cooperation in the Baltic macroregion as a mechanism of managing the innovative development of regional economy.doi:10.5922/2079-8555-2011-2-7 fatcat:uqo4e4tjynagpe4bgzdvjv3zpa