A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf
.
TRPP2 and autosomal dominant polycystic kidney disease
2007
Biochimica et Biophysica Acta - Molecular Basis of Disease
Mutations in TRPP2 (polycystin-2) cause autosomal dominant polycystic kidney disease (ADPKD), a common genetic disorder characterized by progressive development of fluid-filled cysts in the kidney and other organs. TRPP2 is a Ca 2+ -permeable nonselective cation channel that displays an amazing functional versatility at the cellular level. It has been implicated in the regulation of diverse physiological functions including mechanosensation, cell proliferation, polarity, and apoptosis. TRPP2
doi:10.1016/j.bbadis.2007.01.003
pmid:17292589
fatcat:jcsh375e4jcbliim2ovyoc5jjm