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Insulin resistance (IR) is identified as an impaired biologic response to insulin stimulation of target tissues, primarily liver, muscle and adipose tissue. Insulin resistance impairs glucose disposal, resulting in a compensatory increase in beta-cell insulin production and hyperinsulinemia. There was a positive correlation between insulin, homeostatic model assessment of insulin resistance (HOMA-IR) values and acne vulgaris. Nesfatin-1 is a novel peptide hormone that suppresses appetitedoi:10.21608/bjas.2020.135510 fatcat:qwstaw2q7nehhgfikppay2tldq