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Methods We prospectively measured compliance with the guideline in a randomly selected subset. After doing the first cycle, we presented the results locally along with regular education of PICU medical and nursing staff. We compared the total number of blood tests requested and their costs per patient-day in three days-blocks pre-intervention (October 2019) and post-intervention (January 2020). Results Prospective audit data showed compliance with the guideline in 8 of 24 (33.3%) patient-daysdoi:10.1136/bmjpo-2021-rcpch.75 fatcat:zzsssvhxm5bznpdl6ec5xlx5s4