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Predicting Pathological Complete Response (Pcr) After Stereotactic Ablative Radiation Therapy (Sabr) of Lung Cancer Using Quantitative Dynamic [18f]fdg Pet and Ct Perfusion: A Prospective Exploratory Clinical Study
Background:Stereotactic ablative radiation therapy (SABR) is effective in treating inoperable stage I non-small cell lung cancer (NSCLC), but imaging assessment of response after SABR is difficult. This prospective study aimed to develop a predictive model fortrue pathologic complete response (pCR) to SABR using imaging-based biomarkers from dynamic [18F]FDG-PET and CT Perfusion (CTP).Methods:Twenty-six patients with early-stage NSCLC treated with SABR followed by surgical resection weredoi:10.21203/rs.3.rs-35238/v1 fatcat:bfiizz4y4jf2tfaep3dqqbpegy