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Advanced Technologies and Mechanisms for Yeast Evolutionary Engineering
2020
Microbiology and Biotechnology Letters
In vitro evolution is a powerful technique for the engineering of yeast strains to study cellular mechanisms associated with evolutionary adaptation; strains with desirable traits for industrial processes can also be generated. There are two distinct approaches to generate evolved strains in vitro: the sequential transfer of cells in the stationary phase into fresh medium or the continuous growth of cells in a chemostat bioreactor via the constant supply of fresh medium. In culture,
doi:10.48022/mbl.2009.09004
fatcat:rtrxpmvpqbh6tlybkswpwqpc3e