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Induction of Ventral Spinal V0 Interneurons from Mouse Embryonic Stem Cells
The ventral spinal population of V0 interneurons (INs) contribute to the coordinated movements directed by spinal central pattern generators (CPGs), including respiratory circuits and left-right alternation. One challenge in studying V0 INs has been the limited number of cells that can be isolated from primary sources for basic research or therapeutic use. However, derivation from a pluripotent source, such as has been done recently for other IN populations could reduce this issue. However,doi:10.1101/2020.08.06.237115 fatcat:kjpq2epijncxlaguloo7q37cra