Pan-resistant Candida auris: New York Sub-cluster Susceptible to Antifungal Combinations [article]

Brittany O'Brien, Jiali Liang, Sudha Chaturvedi, Jonathan Jacobs, Vishnu Chaturvedi
2020 bioRxiv   pre-print
Four pan-resistant Candia auris strains from New York outbreak were 100% inhibited in vitro by combinations of two antifungal drugs using fixed concentrations achievable in vivo. Pan-resistant C. auris strains have mutations in eleven gene targets associated with major antifungal drugs, and constituted a distinct sub-cluster among NY strains.
doi:10.1101/2020.06.08.136408 fatcat:gh4f3sjli5aklnjqb5ab26jehe