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Evolution of the genetic architecture of local adaptations under genetic rescue is determined by mutational load and polygenicity
[article]
2020
bioRxiv
pre-print
Inbred populations often suffer from heightened mutational load and decreased fitness due to lower efficiency of purifying selection at small effective population size. Genetic rescue (GR) is a tool that is studied and deployed with the aim of increasing fitness of such inbred populations. The success of GR is known to depend on certain factors that may vary between different populations, such as their demographic history and distribution of dominance effects of mutations. While we understand
doi:10.1101/2020.11.09.374413
fatcat:gk2ilb3dejal5i34qbeuqj7kd4