Title In vivo MRI study of the visual system in normal, developing and injured rodent brains

Kk; Mm; Xing, Zhou, Iy; Chow, C; Lau, So, Wu, Ex Citation
2010 Annual International Conference Of The Ieee Engineering In Medicine And Biology Society   unpublished
Issued Date 2010 URL http://hdl.handle.net/10722/142309 Rights IEEE Engineering in Medicine and Biology Society Conference Proceedings. Copyright © IEEE.; This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.; ©2010 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers
more » ... bution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE. Abstract-This paper demonstrated our recent use of contrast-enhanced MRI, diffusion tensor/kurtosis imaging, proton magnetic resonance spectroscopy, and functional MRI techniques, for in vivo and global assessments of the structure, metabolism and function of the visual system in rodent studies of ocular diseases, optic neuropathies, developmental plasticity and neonatal hypoxic-ischemic brain injury at 7T. Results suggested the significant values of high-field multiparametric MRI for uncovering the processes and mechanisms of developmental and pathophysiological changes systematically along both anterior and posterior visual pathways, and may provide early diagnoses and therapeutic strategies for promoting functional recovery upon partial vision loss.