Noninvasive Measurement of Pulmonary Capillary Wedge Pressure by Speckle Tracking Echocardiography [chapter]

Masanori Kawasaki
2016 Echocardiography in Heart Failure and Cardiac Electrophysiology  
The severity of left-sided heart failure can be evaluated by pulmonary capillary wedge pressure (PCWP) because PCWP reflects left ventricular (LV) filling pressure. Owing to developments in echocardiographic technology, speckle tracking echocardiography (STE) has allowed automatic construction of time-left atrial (LA) volume (LAV) curves. Thus, we developed a novel index based on a combination of LAV and LA function that would estimate PCWP using STE. The following regression equation described
more » ... the relationship between PCWP that was obtained by right-heart catheterization and active LAEF/minimum LAV index (volume was indexed to body surface area: LAVI) in the patients with sinus rhythm: PCWP = 10.8-12.4 [log 10 (active LAEF/minimum LAVI)] (r = −0.86, p <0.001) (measurements from the apical 4-chamber view). We defined this index [log 10 (active LAEF/minimum LAVI)] as the kinetics-tracking index (KT index). The PCWP estimated by the KT index (ePCWP) had a strong correlation with PCWP obtained by right-heart catheterization (r = 0.92, p <0.001). The ePCWP measured by STE could be a useful parameter to improve clinical outcomes in patients with heart failure.
doi:10.5772/64864 fatcat:lwiicks7kbbrxpxemxwx5rvdka