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Recent work has introduced biocircuit architectures that exhibit robust oscillatory behavior in organisms ranging from cyanobacteria to mammals. Complementary research in synthetic biology has introduced oscillators in vivo and in vitro suggesting that robust oscillation can be recapitulated using a small number of biochemical components. In this work, we introduce signaling crosstalk in biocircuits as a consequence of enzyme-mediated biochemical reactions. As a motivating example, we considerdoi:10.1109/cdc.2012.6425854 dblp:conf/cdc/YeungKYGM12 fatcat:hym73fu5ajdfpcy32z66kzlxqu