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Motivation: The problem addressed in this paper is the prediction of splice site locations in human DNA. The aims of the proposed approach are explicit splicing rule description, high recognition quality, and robust and stable 'one shot' data processing. Results: These results are achieved by means of a new learning algorithm [BRAIN (Batch Relevance-based Artificial INtelligence)], described in the paper, inferring Boolean formulae from examples, and by considering the splicing rules asdoi:10.1093/bioinformatics/14.8.676 pmid:9789093 fatcat:7d35uyjtpbdr5aes5cqvuhvfha